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The case described is that of an African 24 year old and Para 2. This paper presents a case of adenocarcinoma of the rectum in which the history strongly suggested a radiation-induced carcinoma 12 years after initial radiotherapy for carcinoma of the cervix. Relation between drug resistance and antigenicity among norakin-resistant mutants of influenza A (fowl plague) virus. Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25. Various in vivo and in vitro studies on allergenic pollen are shown and discussed.

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A second locus on chromosome 14 contains pseudogenes of RBM8A and the type II GnRH receptor and probably originated from the chromosome 1 locus by retrotransposition. Here, we used the dosage compensation mechanism (DCM) of Drosophila to demonstrate that chromosome-wide gene dosage imbalance contributes to the deleterious effects of CIN-induced aneuploidy and its pro-tumorigenic action. Optimization of large-scale pseudotargeted metabolomics method based on liquid chromatography-mass spectrometry.

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Here, we describe a human cell-based screening assay, optimized by varying multiple experimental parameters that resulted in an assay that was used to demonstrate full and potent neutralization by the parental, chimeric and humanized antibodies. Although day 2-3 and OPU-day measurements of serum glycodelin levels were not significant in predicting clinical pregnancy, the pattern of serum glycodelin seems different in GnRH-antagonist controlled cycles than natural and GnRH-agonist controlled cycles. DOX-EBP could be used for receptor-targeted chemotherapy with less toxicity and greater efficacy of tumor cells overexpressing EGFR. We employed a narrative synthesis design to analyse the findings sections of all papers as the methods of the various studies did not permit the pooling of data.

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The formulations were tested and found to be physically stable throughout the entire study. Light and electron microscopy, combined with time-lapse videomicroscopy, revealed that cells organized on a tesselated network of aligned basement membrane matrix that was generated by tension forces of cellular traction. Drug ion-selective electrodes made with hetero-poly anion as exchange site exhibit better performances than the respective electrodes of conventional tetraphenylboron type, yielding low detection limits and fast responses. Either supraacetabular or partial acetabular resection was virtually planned in a hemipelvis using engineering software. As axonal transport is dependent on the integrity of the neuronal cytoskeleton, we have studied the way in which rat brain and nerve cytoskeletal proteins are altered in experimental diabetes.

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Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring. EFFECT OF PHOTOPERIODS ON EARLY GROWTH OF GONADS AND ON POTENCY OF GONADOTROPINS OF THE ANTERIOR PITUITARY IN COTURNIX. Nevertheless, uptake of PFCs into the spleen was consistently greater than into the liver, irrespective of formulation injected. Risk-benefit assessment of methotrexate in the treatment of severe psoriasis. This article reviews key preclinical studies and their results that formed the basis for introduction into clinical trials.

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The hearts were then subjected to 60 minutes of LCx occlusion and 5 hours of reperfusion. Ventricular tachycardia was similarly inducible during all three periods. The effect of UP location is, however, smaller than that predicted by the original cohort theory (that recognition occurs exactly at the UP). HAC was evaluated in terms of stability, cytotoxicity, permeation enhancement, controlled drug release and mucoadhesiveness.

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Hydrazine derivatives of isonicotinic acid in the treatment of tuberculosis. Fibronectin antisera detected an approximately 220 kDa protein in western blots of adult and fetal skin. The SCAN, Staggered Spondee Word test (SSW), Competing Sentence test, Peabody Picture Vocabulary Test (PPVT), and the Clinical Evaluation of Language Fundamentals-Revised (CELF-R) were administered to 155 children between the ages of 6 and 15 years. HCF-1 and the related protein HCF-2 form an HCF protein family in humans that is related to a Caenorhabditis elegans homolog called CeHCF. In a specificity test that used purified DNA from Old World and New World Leishmania, the assay recognized all parasites isolated from patients with visceral leishmaniasis, except for 2 isolates of Leishmania colombiensis from Venezuela and 1 isolate from Brazil.

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Following the injection of 3-5 microliters of horseradish peroxidase or Fast Blue into the left adrenal medulla, labelling of neurons in the vagal sensory ganglia of rats and guinea-pigs has been demonstrated in all cases. This suggests that PTEX88 likely plays a specific direct or indirect role in mediating parasite sequestration rather than making a universal contribution to the trafficking of all exported proteins. The aim of the present paper was to discuss the conventional treatment against Candida albicans infections. The study shows that mAs and major organ doses for paediatric CT scans in Great Britain began to decrease around 1990.

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Survival rate of moderate- and high-risk patients is yet to be improved. Thus, these two structures could be functionally differentiated for the first time. Pregnancy tumour of the external auditory canal: treatment in clinic. Exposure to WBV among operators of mining vehicles may be a serious health and safety problem in the mines studied.

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Aneurysma spurium as a complication after diagnostic and interventional femoral artery puncture The authors represent a further program-system for computer aided data processing of the results from the systematic dental examinations in children. A study of intercellular communication of human transitional cell carcinoma cell lines

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Investigation of permeability of intranasal formulations using Side-Bi-Side horizontal diffusion cell The early and late mortality rates as well as the morbidity rates (both neurological and splanchnic) were nil. Regulatory mechanisms, expression levels and proliferation effects of the FUS-DDIT3 fusion oncogene in liposarcoma. Retrospective analysis of medical documentation of the Tobolsk integrated prosectorium in 1950-1987 was made. As such, we hypothesised that participants with signs of neuropathic pain would report higher levels of psychological distress and diminished self-rated health compared to those without a neuropathic component.

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While valuable information was identified by the study, the findings raised some serious questions about productivity, staff attitudes, and work ethics. Relative risks of stroke per unit of exposure were obtained from the Global Burden of Disease Study 2010. First, all of the completely sequenced eukaryotes harbor introns in the genomic structure, whereas no prokaryotes identified so far carry introns. An efficient salt-chloroform extraction of DNA from blood and tissues.

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We conclude that cyclic stretch of ECs results in activation of PKC, which may be responsible for mediating the effects of cyclic stretch on EC growth. Taiwan is facing a rapid change in the composition of its population.

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Physical compared to mental diseases as reasons for committing suicide: a retrospective study. Phospholipid-containing toxic malaria antigens induce hypoglycaemia.

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BL21 (DE3) as the host strain was utilized for self-induced expression of the protein. Both the introduction and the repair of many types of DNA lesions are heterogeneous with respect to chromatin structure and/or gene activity. A universal working definition of social functioning as an overarching construct is recommended. Studies have demonstrated that microRNAs (miRNAs) and their target genes are involved in the formation of atherosclerosis and that atorvastatin might reduce atherosclerotic plaques by regulating the expression of miRNAs. There is no other study in literature investigating these activities for CRC patients.

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Isosorbide dinitrate decreased platelet reactivity to ADP (p less than 0.001), increased platelet sensitivity to PGI2 (p less than 0.01) while the production of TXB2 from exogenous arachidonic acid substrate and from endogenous substrate were both significantly reduced. Can a simple question predict prolonged uroflow lag times in children? Discriminating contrast discontinuities: asymmetries, dipper functions, and perceptual learning.

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Cytokine-release kinetics of platelet-rich plasma according to various activation protocols. Analysis of bacteria by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) often relies upon sample preparation methods that result in cell lysis, e.g. Function of the catalytic domain of poly(3-hydroxybutyrate) depolymerase from Pseudomonas stutzeri.

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Tissue Doppler imaging (TDI) is a new echocardiographic technique that directly measures velocities in the myocardium. The initiation of ART has dramatically changed the clinical manifestation of HIVAC in high income countries from one of severe, left ventricular systolic dysfunction to a pattern of subclinical cardiac dysfunction characterized by abnormal diastolic function and strain. Western blot demonstrated gp80 protein (IL-6 receptor a subunit) in all pancreatic cancer cell lines except in AsPC-1. Unusual case of associated pulmonary echinococcal cysts and bilateral tuberculosis In this respect, pinned domain walls in magnetic nanowires are particularly attractive.

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The expressed proguanylin failed to elevate cyclic GMP concentrations in human colonic T84 cells, but acetic acid treatment of pro-guanylin activated it and resulted in large elevations of cyclic GMP. New look in the concept of the rehabilitation of the mentally retarded in a state institution. One of the important medical problems is infectious diseases such as HIV and hepatitis which annually causes the death of many people. Analysis of rates of primary cesarean section by level of perinatal designation and of individual hospitals with rates in excess of 20 percent show the increased utilization of cesarean sections between 1967 and 1986. Forskolin (10-20 microM) increased i(f), and ACh at 1 microM partially reversed this action of forskolin.

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Traditionally, a one-sided hypothesis is used to make statistical inference, and the actual Type I error rate has to be computed over the parameter space of the null hypothesis. On admission, physical examination showed markedly distended abdomen due to ascites and hepatomegaly.

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Late orchiectomy, in contrast, had no significant effect on the progression of glomerular sclerosis or proteinuria but did significantly reduce the blood pressure and marginally increase the excretion of urine kallikrein. CORRECTION OF CICATRICIAL STENOSIS IN ESOPHAGOJEJUNAL ANASTOMOSES The constituents denoted 85A, 85B, and 85C are encoded by three genes located at different sites in the mycobacterial genome and show extensive cross-reactivity as well as homology at amino acid and gene levels. Urban surface water pollution problems arising from misconnections.

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An anatomic study was carried out on 24 fresh upper limbs infused with colored and radiopaque solutions before or after flap elevation. This additional flexibility, which likely results from a significant relative chain-end contribution to the average chain dynamics, could be related to the strong structural polymorphism of the investigated oligonucleotides. The herbicide diuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea) is used in many agricultural crops and non-crop areas worldwide, leading to the pollution of the aquatic environment by soil leaching.

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Time and dose dependent effects of oxidative stress induced by cumene hydroperoxide in neuronal excitability of rat motor cortex neurons. The specific advantages of a number of integrated optical systems, consisting of optical probes of various shapes and materials, coupled to a number of optical fibers are described. Immunohistochemical demonstration of CD20 in diffuse large B-cell lymphoma (DLBCL) is prerequisite not only for the diagnosis but also for assigning patients to rituximab-containing chemotherapy. It was established that the racemates of primary and secondary amines (p-fluoro-amphetamine, methamphetamine, p-fluoro-methamphetamine) hydrochloride do not form racemic compounds but crystalline as conglomerates, at the same time tertiary amines like selegiline and p-fluoro-selegiline hydrochlorides do. This study sought to employ a conventional TTO approach to obtain values for a selection of Child Health Utility 9D (CHU9D) health states from a sample of young adults aged 18-29 years and to compare with the values generated from application of the original UK adult standard gamble scoring algorithm and the Australian adolescent scoring algorithm.

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Distribution and restoration of minerals of the bones in relation to the processes of structural reconstruction Derivatization conditions such as temperature, time and triethylamine catalyst were tested. Daily changes in serum CSF levels were also examined in a patient with autoimmune neutropenia, and it was found that the peripheral neutrophilic granulocyte count changed almost in parallel with the serum G-CSF level but not with GM-CSF, following the pattern with a delay of about 4-5 h, suggesting the possibility that G-CSF mainly regulates peripheral neutrophil circulation. These results suggests that gut-derived substances sensitive to polymyxin B sulfate may contribute to activation of hepatic macrophages after partial hepatectomy in rats.

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III) Brain gene targeting technology enables widespread expression of an exogenous gene throughout the central nervous system following an intravenous injection of a non-viral therapeutic gene. The effect of the concentration of curing salts, the nature of the probiotic culture (free or immobilized Lactobacillus casei ATCC 393 on wheat grains) and the ripening time on the generation of volatile compounds in probiotic dry-fermented sausages was investigated. These results suggest that a short-lived rRNA precursor is synthesized and processed at comparable rates in both bloodstream and insect stages of the parasite. Chronic heart failure is a dominant problem not only in cardiology but also from the political and economical points of view in civilized countries. Area under the receiver operating characteristic curves (AUC) of individual UF parameters was compared.

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A novel feature of this work is its use of postal code random effects from two other independent datasets collected in the annual national monitoring by questionnaires of winter losses of honey bees in the Netherlands. Role of the bacteria of the digestive tracts of mammals and birds in the synthesis of vitamins

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This work also brings to the forefront the important role that interfacial mechanics may play in bacterial suspensions with free surfaces. High-affinity calcium-stimulated, magnesium-dependent adenosine triphosphatase in Trypanosoma cruzi.

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This novel approach to SCD repair could have advantages over current techniques. Treatment usually is aimed at symptom relief until delivery, as the eruption usually resolves rapidly in the postpartum period. We remark that a routine extension of the proposed methodology in this paper can be applied to the substitution of hidden spaces although the detailed illustration is omitted.

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It occurs over a wide range of long-chain to short-chain ratios and occurs with 1-palmitoyl-2-stearoylphosphatidylcholine and dimyristoylphosphatidylcholine as well. The aim of this study is to quantify shoulder and rotator cuff muscle forces during driving in different postures. The poisonous principle and histology of Gloriosa virescens Lindl.