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Digobal (Digoxin)

Digobal is used to treat heart failure, usually along with other medications. It is also used to treat a certain type of irregular heartbeat (chronic atrial fibrillation). Treating heart failure may help maintain your ability to walk and exercise and may improve the strength of your heart. Treating an irregular heartbeat can decrease the risk for blood clots, an effect that may reduce your risk for a heart attack or stroke. Digobal belongs to a class of medications called cardiac glycosides. It works by affecting certain minerals (sodium and potassium) inside heart cells. This reduces strain on the heart and helps it maintain a normal, steady, and strong heartbeat.

Other names for this medication:
Digoxin, Lanoxin, Digibind, Digitek, Digobal, Digossina, Digoxine, Eudigox, Lanicor, Sigmaxin, Vidaxil,

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Furthermore lymphocyte migration throughout various organs in the body including skin depend on a variety of molecular and cellular interactions. The major procedures include: (1) chemical profiling and structural assignment of herbs by liquid chromatography with mass spectrometry (LC-MS), (2) quantification of major components by LC-MS, (3) probabilistic neural network (PNN) model to calculate contributions of components toward species classification, (4) discovery of minimized number of chemical markers for quality control. Moreover, enriched transitional B cells showed a cell-autonomous defect leading to excessive apoptosis. The management of asthma in pre-school children often presents physicians with challenging problems.

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ISOLATION AND STUDY OF A FRAGMENT OF HUMAN SERUM ALBUMIN CONTAINING ONE OF THE ANTIGENIC SITES OF THE WHOLE MOLECULE. Impacted stapler pin in fractured maxillary central incisor with open apex: Advanced endodontic management using biodentine as innovative apical matrix.

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Here, we have used transgenesis in zebrafish in order to define regulatory elements that drive lhx5 expression in the forebrain. In the current study we explored how risk- and protective factors such as cognitive control, adaptive and maladaptive emotion regulation, residual symptomatology, and resilience relate to one another in a remitted depressed (RMD) sample. One possible explanation was that premature phosphorylation of Rad9 caused its dissociation from 9-1-1 at stalled replication forks, resulting in their collapse and prolonged activation of the S-phase checkpoint. The abdominal organs do not demonstrate isomerism, and they show variable features when compared to the isomeric atrial appendages. First Images of a Three-Layer Compton Telescope Prototype for Treatment Monitoring in Hadron Therapy.

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Chemical, biologic, radiologic, nuclear, and explosive (CBRNE) incidents require specialized training. Overall, the results of therapy were disappointing as all the 15 patients died within 6 months of diagnosis. Significance of internal medicine for geriatrics--independent gerontology Limitations of transoesophageal echocardiography in patients with focal cerebral ischaemic events.

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MEFV gene, causing FMF, encodes pyrin that is associated with the interleukin-1 (IL-1) related inflammation cascade. The purpose of this study was to evaluate whether fluoride applied in different forms has different short-, mid-, and long-term effects on the growth of the bacteria Streptococcus mutans.

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Shift in antioxidant parameters, lactate dehydrogenase (LDH) together with morphological and histopathological changes were investigated. The intricacies of cooperation and competition between microorganisms are poorly investigated for particular components of the gut microbiota. This paper describes the sequence of steps leading to regional control success. N 2 O-O 2 inhalation sedation produces adequate sedation with vital signs within normal limits and treatments successfully completed. Tormentic acid (TA), a triterpene isolated from Rosa rugosa, has been reported to exert anti-inflammatory effects.

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Patients with microbiologically confirmed tuberculosis of the central nervous system and whose management included surgery are described. Two new species of Heligmoptera Nadtochiy, 1977 (Nematoda: Trichostrongylina: Heligmosomoidea) from myospalacine rodents in China (Gansu), with a redefinition of the genus. Psychological testing revealed the participation and features of emotional traits and personality of patients in the development and course of various diseases.

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To evaluate the immunologic effects of general anesthesia with the hypnotic agent propofol and the opioid fentanyl, two drugs used frequently in anesthesia, we studied 30 patients undergoing elective orthopedic surgery before and during narcosis. Other than SSBs, improvements in food group intake did not differ by intervention group in overweight Mexican women. No correlation between ras, c-myc and c-jun proto-oncogene expression and prognosis in advanced carcinoma of cervix.

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Retinoic acid receptors are nuclear transcription factors that play a key role in retinoid physiology. Growth inhibition, cell cycle arrest, induction of p53 and p21 mRNA and protein, and cdc2 phosphorylation and kinase activity were studied in treated cells from the H460 lung cancer line and p21 and p53 knockout cells of the HCT 116 colon cancer line.

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Most emergency medical services are provided by Princess Margaret Hospital and Rand Memorial Hospital located respectively on those 2 islands. These results suggest that the expression level of AT1B mRNA in the adrenal gland depends on the activity of the renin-angiotensin-aldosterone system (RAAS) and both receptor subtypes mediate contraction and hypertrophy of the smooth and cardiac muscles via the RAAS. A large variation in research methodology, stretching techniques, duration of stretch, and repetition of exercises was found. This study aimed to examine, prospectively: (1) the frequency, (2) patterns of co-morbidity, (3) trajectory, and (4) risk factors for psychiatric disorders during the first 5 years following TBI. Preoperative diagnosis was established by computerized axial tomography.

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Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake. Young mice were maintained on a basal diet composed of meat, which is poor in both manganese and calcium. These new methods allow for a more appropriate way to address the confound of many gait measures being velocity dependent. This study aimed to examine whether fear of cancer recurrence (FCR) was related to two important health behaviours (physical activity and smoking) in a large sample of colorectal cancer patients.

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Association of rs2228570 polymorphism of vitamin D receptor gene with degenerative disc disease: a meta-analysis involving 2947 subjects. Using a computerized goniometer type instrument (Acufex KSS), knee flexion, axial tibial rotation and anterior-posterior tibial displacement were simultaneously recorded, while the runners underwent tests of static as well as dynamic knee joint laxity. This study provides data that challenge the concept of targeted elimination of CSC by ionophore antibiotics. During the development of binocular maps in the tectum of Xenopus laevis, axons that relay input from the ipsilateral eye via the nucleus isthmi undergo a prolonged period of shifting connections.

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Treatment of 104 cases suffering from cervico-spinal hypertension with rotation-reduction method--observation of the long-term effect. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) Fat and amino acids stimulate the secretion of bicarbonate only when the attachments of the pancreas to the stomach and duodenum are intact. CASE RECORDS of the Massachusetts General Hospital: weekly clinicopathological exercises: case No. Improvements were also realized using surgical voice restoration during and after laryngectomy.

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Pharmacokinetic modeling of the lung burden from repeated inhalation of nickel aerosols. While the latter was induced by the presence of vertical untransparent surfaces.

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Role of MAP kinase pathways in primitive neuroectodermal tumors. There were 156 casualties with dominant Chest and Abdominal injuries.

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Influence of prostatic disease and prostatic manipulations on the concentration of prostate-specific antigen. However, its catalytic impact on transition-metal oxide thin films, such as perovskites, is not widely understood.

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Secondary outcomes were quality of glottis visualization, time until successful intubation, and risk of oropharyngeal complications. The epitope recognized by one of the anti-denatured H-chain Moabs was mapped on the C-terminal helix of ferritin.

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Uptake of PrEP and condom and sexual risk behavior among MSM during the ANRS IPERGAY trial. However, the x-ray densitometry method he employed cannot be applied to living people. How We Manage Hyperferritinemic Sepsis-Related Multiple Organ Dysfunction Syndrome/Macrophage Activation Syndrome/Secondary Hemophagocytic Lymphohistiocytosis Histiocytosis. After correction of the cDNA frameshifts, a deduced amino acid sequence corresponds exactly to the data established at the protein level.

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DNA barcoding confirms the presence of Hydria cervinalis (Scopoli, 1763) in the Iberian Peninsula (Lepidoptera: Geometridae: Larentiinae). The possible role of the heat shock-related proteins in this important environmental transition is considered. It is shown that the proposed device can handle the wash and dielectrophoretic separation successfully.

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We describe 11 patients in whom middle fossa vestibular neurectomy was performed following failure of a retrolabyrinthine vestibular neurectomy. Serum concentrations of immunoglobulin G2 (IgG2) are elevated in localized aggressive periodontitis (LAgP) patients, and secretory products of monocytes from LAgP patients enhance IgG2 responses of lymphocytes from healthy subjects. To assess the biomechanical changes of collagen cross-linking on keratoconic corneas in vitro. In this review, the role of cadherin expression was focused on, both in development and carcinogenesis, paying particular attention to mechanisms involved in its down-regulation. Furthermore, in a mouse model, immune responses played an important role in determining the local and systemic therapeutic efficacy of radiotherapy that could be augmented by the immune checkpoint blockade.

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Melatonin (0.1-10 mg/kg i.p.) dose-dependently decreased the levels of dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC), as well as the DOPAC/dopamine ratio, in chick retina but not in forebrain. Our previous studies have shown that dietary xylitol supplementation protects against the loss of bone mineral after ovariectomy.

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Abdominal trauma is responsible for most genitourinary injuries. Suspensions, culture supernatants and bacterial lysates of Actinomyces viscosus, Actinomyces naeslundii and Actinomyces odontolyticus were investigated for their actions upon C. The concept of carcinogenesis as a multistep process suggests the possibility of blocking or reversing the progression to invasive cancer with systemic treatment. Whether all or only part of TSH action is mediated by cAMP and the cAMP-dependent protein kinase remains to be determined. This test showed good reproducibility, better than the classical mice serum neutralization test (SN).

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The treatment device was a four-channel computer-controlled hyperthermia system. These results suggest that the immune response of humans to paramyosin may play a role in natural resistance to schistosome infection, and that an elevated antibody level against this antigen may be a useful correlate of drug-induced cure. Crystal structure of (Z)-3-allyl-5-(3-bromo-benzyl-idene)-2-sulfanyl-idene-1,3-thia-zolidin-4-one. A comparison of biomarker responses in the earthworm Aporrectodea caliginosa to the organophosphorus insecticides diazinon and chlorpyrifos.

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Blood cell count, hemoglobin (Hb), hematocrit (Hct), serum bilirubin, transaminases, urea, and creatinine concentrations were evaluated. Since both cell types are in close contact with one another in the damaged nervous system, we have examined the growth of axons on cultures which contain both astrocytes and oligodendrocytes.

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The metastasis is an incidental finding on imaging after having some vague symptoms. Present status and controversy of treatment for renal cell carcinoma violations of pitch) of the last word, in order to measure the evoked activation in a magnetoencephalographic (MEG) experiment. In multivariate analysis a significant risk of breast cancer was found when there was a family history of breast cancer in Models 2 and 3 but not in Model 1. This study was designed to measure these blood flow velocity variables both proximal and distal to a significant coronary artery stenosis in patients undergoing coronary angioplasty.

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These results suggest that colon epithelial cells can contribute to local inflammatory responses by releasing CSFs and thus extend the life span of local leukocytes. Magnetic resonance imaging (MRI) and magnetic resonance spectroscopic (MRS) findings in 3-methylcrotonylglycinuria presenting with acute metabolic decompensation in a previously healthy 7-year old female are described. Immunostimulated peritoneal macrophages of mice and rat have been demonstrated to produce L-arginine-derived nitrogen oxides. Rats were trained in a Skinner box to approach the food cup when a distinct click was sounded.

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Response of slow and fast muscle to hypothyroidism: maximal shortening velocity and myosin isoforms. Unloaded shortening after a quick release of a contracting, single fibre from crayfish slow muscle. Centbucridine (9-n-butylamino-1,2,3,4-tetrahydroacridine) is a new potent local anaesthetic. It has been proved that the use of mechanical ventilation (MV) increased the development of delirium and POCD.

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Acquired syphilis has become an overlooked cause of posterior uveitis including chorioretinitis. Islet transplantation under the kidney capsule is a potentially effective therapy to correct several diabetes-induced abnormalities of insulin signaling in cardiac muscle but does not restore the responsiveness of all signaling reactions to insulin. C60 fullerene localization and membrane interactions in RAW 264.7 immortalized mouse macrophages.

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Adult sexual orientation in relation to memories of childhood gender conforming and gender nonconforming behaviors. Urinary excretion of urate and xanthines was significantly increased (p less than 0.001) only in the cirrhotics after the fructose/galactose load. Herein, kinase activities seem to play an important role in Treg fine tuning. The present study demonstrates that there are a considerable number of immunoreactive prolactin (PRL) cells that are also stained with antibody against the alpha-subunit when adjacent sections are immunocytochemically examined.

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Excreta disposal behaviour and latrine ownership in relation to the risk of childhood diarrhoea in Sri Lanka. This will specifically target young men before or shortly after their sexual debut when they may still be free of HIV and HSV-2 infections.

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For this study we developed a spatially explicit, agent-based model of population growth to represent the complex population dynamics of invasive marine macroalgae with heteromorphic biphasic life cycles. Nonetheless, there is accumulating evidence that suggests the production of these anti-platelet autoantibodies is under the influence of several abnormal lymphocyte-mediated mechanisms, i.e.

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Ureteral access for upper urinary tract disease: the access sheath. Synthetic cannabinoids appear to be associated with potentially dangerous health effects that are more severe than that of marijuana. In a separate parallel study, the nerves were harvested 2 weeks following graft implantation to assess gene expression changes. Using the results from in situ isolation tests, individual force-deflection responses from 132 samples were transformed with a normalization procedure into mean force-deflection properties to describe the nonlinear characteristics.

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Each QD holds two copies of the pRNA three-way junction (pRNA-3WJ) of the bacteriophage phi29 DNA packaging motor. The antagonistic effect of lorglumide on the KCl-induced signals was partly reversed 130 min after drug administration. Therefore, it is concluded that the two-faced method is safer for the double labelling immunoelectron microscopic study. A diagnosis of genital C trachomatis infection was made if any one of the specimens tested reproducibly positive.

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A physiologically based model of 1-nitropyrene metabolism after inhalation or ingestion. A reflection session addressed burnout, distress, and self-care. The relationships between serum cytokine levels and tumor infiltrating immune cells and their clinical significance in colorectal cancer. To carry out this work successfully, we have studied the cytotoxicity effect of FeCl3 towards cell lines usually used for the investigation of enteric viruses.

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Controlling single-molecule junction conductance by molecular interactions. To investigate the relationship between the G to A variant at the--308 bp of the promoter region of tumor necrosis factor-alpha gene (TNF-alpha-P) and the body adiposity, the insulin secretion and action, and the glucose and lipid levels in Chinese population. Alkaline phosphatase activity was localized to the nuclear membrane, the Golgi/endoplasmic reticulum, and the limiting membranes of G cell peptide-secretion vesicles. Have You Ever Seen the Impact of Crossing Fiber in DTI?: Demonstration of the Corticospinal Tract Pathway.

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Aptamers, also known as chemical antibodies, are single-stranded nucleic acid oligonucleotides which bind to their targets with high specificity and affinity. Globally, promoting free and accessible EBP massive open online courses (MOOC) and sharing best practices online and at international forums such as Magnet conferences will help to lead, educate, and mentor nurses with strategies to systematically increase EBP uptake.

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We constructed a mutation which results in the substitution of a highly conserved lysine residue (Lys792) in the presumed ATP-binding site of this kinase-like domain with a glutamic acid codon. In this patient, insufficient constriction of capacitance vessels might have played an important role in activation of an inhibitory reflex from cardiopulmonary mechanoreceptors which caused hypotension and bradycardia. Immunotherapy for multiple myeloma: Current status and future directions.

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Cardiovascular diseases, blood rheology, and dihydropyridine calcium antagonists. Improving treatment adherence for blood pressure lowering via mobile phone SMS-messages in South Africa: a qualitative evaluation of the SMS-text Adherence SuppoRt (StAR) trial. It remains unclear whether telemonitoring approaches provide benefits for patients with heart failure (HF) after hospitalization. In this study, a multifunctional stimuli-responsive amphiphilic peptide was designed and synthesized to self-assemble into nanoparticles capable of co-bearing and -releasing hydrophobic drugs and antisense oligonucleotides for combined therapies. Only for the short-term verbal recall test a statistical significant difference between high altitude and cold eeze coupons sea level was ascertained.

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It is concluded that during hypokinesia bone disorders are predominantly produced by local factors that may increase bone sensitivity to systemic influences. Differential effects of quinidine on transmembrane action dolgit gel cenaclul potentials of normal and infarcted canine Purkinje fibers. In families with ciliopathy phenotypes, mutational analysis using a targeted renal gene panel allows a rapid molecular diagnosis and provides important information for patients, parents and their physicians.

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Brain-derived neurotrophic factor (BDNF) is considered to be implicated in the pathophysiology of BD, but its role as an endophenotype has been poorly studied. Here we examine excitatory synaptic transmission in NAc slices prepared from lovir 800 and alcohol animals displaying sensitization 10-14 days after repeated in vivo cocaine exposure. Experimental pre-emptive analgesia: what value for the clinician?

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The data obtained suggest that the rise of endogenous myocardial enkephalins may have an important role in antiarrhythmic action of adaptation. In the presently used autoimmune model, EAN, the net effect of in vivo treatment baclofen highest dose of gabapentin with SITS resulted in worsening of clinical signs and increased inflammatory cell infiltration in sciatic nerve, whereas the in vitro conductivity of sciatic nerve was not significantly affected by the drug. Low-voltage operation of ZrO2-gated n-type thin-film transistors based on a channel formed by hybrid phases of SnO and SnO2. We report on a female preterm infant with hepatic failure and neonatal tissue siderosis of hemochromatotic type diagnosed by using both histochemistry and atomic absorption spectroscopy. We conclude that sulfide produces a high degree of oxidative stress in cells and tissues, and that cobinamide has promise as a first specific treatment for sulfide poisoning.

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It is difficult to obtain fortamet vs glumetza weight a definite diagnosis and to initiate timely intervention. In case of primary closure there was 1 bile leakage without peritonitis.

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Efficacy of a topical nasal decongestant in different formulations: the effect of viscosity. Additionally, for a median follow-up of 25 months, delayed PSA failure is associated with clinically localized rather than metastatic recurrence, a relationship that may help in selection for local salvage therapy. Complications were minor or transient including one patient with snoring. The sources were strictly contralateral for PS but bilateral for ABD contractions. The present apix action photography using manual camera study highlights the fact that pathologists must carefully investigate the histopathological characteristics of liposarcomas in order to obtain an accurate diagnosis.

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The apparent binding constant of LBT with calf thymus DNA has been determined as 1.67 x 10(6) L/mol by ethidium bromide displacement method. Although there have been few studies on their use in elderly subjects, the available data suggest the efficacy and safety of HMG-CoA reductase inhibitors in diclofenac potasico 50 mg calox de costa similar to that established for younger age groups. Women were randomized to physical therapy (PT) for UI or osteoporosis education. So it is important to study infectious diseases parametric models. The resulting structure suggests probable substrate cleavage preferences.

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Taking into account the combined effect of the density of eggs and the dissolved oxygen concentration, we increase the accuracy of analysis of the experimental results and improve the interpretation of the results. Clinical decision-making for coronal caries management in the permanent dentition. Liver weight increased in TCE-exposed mice but there was no correlation between this mediklin cair review effect and that on nerve regeneration. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. The amounts of IL-2 in the supernatants of two and four passages transfected keratinocytes were 27.7 U/ml and 15.0 U/ml, respectively.

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Recent Advances: Technologies being developed for the management of wounds are rapidly expanding. The atypical effect of a hearing aid on one patient with congenital deafness. Cardiac maxit capital canada abnormalities were clinically detected in 53 patients, all of which were confirmed or documented by echocardiography. Positive immunohistochemical reaction for Actin, Desmin and Vimentin, negative for S100.