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The guinea-pig vas deferens is a quiescent muscle which after castration undergoes atrophy and shows spontaneous contractions preceded by membrane spike activity. To clarify the physiological role of this tissue kallikrein, we investigated its effects on the spontaneous metastasis and tumor growth of Lewis tumors (3LL). These observations suggest that the cellular mechanism of action of LD Ara-C is different from that of HD Ara-C, but do not favour a differentiating action of LD Ara-C. As a control, samples from healthy donors and patients with iron deficiency anemia were also collected. Patients were followed for at least 6 months to record the occurrence of MACE.

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In-vitro fertilization in cases with severe sperm defect: use of a swim-across technique and medium supplemented with follicular fluid. The new method is tested on an in situ deformed Si single-crystal, for which the prescribed stress distribution has been calculated by finite-element analysis.

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When required, anti-aggregating drugs may be associated with anagrelide, since it has no effect on platelet function. First structure of archaeal branched-chain amino acid aminotransferase from Thermoproteus uzoniensis specific for L-amino acids and R-amines. Blood chemical analysis, urinalysis, immunologic tests--interpretation of the data

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We have been engaged in the development of asymmetric conjugate addition reactions of lithium thiolates, organolithiums and organocopper reagents under the control of external chiral ligands and we have also developed an efficient asymmetric Horner-Wadsworth-Emmons (HWE) reaction using an external chiral Ligand. The RPI is a new quality improvement tool for family medicine residency programs. Effect of antineoplastic agents on smooth muscle cell proliferation in vitro: implications for prevention of restenosis after transluminal angioplasty. Subsequently, it was demonstrated that the esterase substrate p-nitrophenylbutyrate is hydrolyzed by phenmedipham hydrolase.

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The carotid sinus complex and epithelial body of Varanus varius. The hope is that these expectations are met, and that all drugs being developed will offer new and improved treatment options for SCLC patients. Solutions for the problem of dealing with difficult patients: difficult but lovable patients Editing added 259 uridines and removed 46 uridines to produce an approximately 574-nucleotide mature mRNA. In turn, these factors facilitate the specialization and strengthening of connectivity in networks supporting the transition to adult levels of cognitive control.

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Diastolic regional wall motion asynchrony in patients with hypertension. The clinical profile of neurotoxicity caused by immunosuppression has changed. Both groups of patients were interviewed on the fourth day following admission to hospital and again at 2 and 6 months after discharge. An enzyme-linked immunosorbent assay (ELISA) was developed for measurement of the antibody response to exocellular protein antigens of Staphylococcus aureus.

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This cascade reaction uses readily available and cheap sodium azide as a nitrogen source to gave 3-azido furoindolines and pyrrolidinoindolines under mild reaction conditions. Novel molecular diagnostic tools for malaria elimination: a review of options from the point of view of high-throughput and applicability in resource limited settings. In three cases the source of contagion was horses, in two it was cattle and in one case it was another person. In adult and aged rat hearts, dexamethasone treatment induced a slow depolarization and a plateau in the region of overshoot.

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During the first test (T1) the pacemaker was programmed to the DDD mode and heart rates were recorded every 15 to 30 seconds during exercise and 30 minutes after exercise. We report on a case occurring in a 3-year-old child with congenital multiple melanocytic nevi.

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Recombinant human BMP-9 potently induced alkaline phosphatase (ALP) activity, mineralization, and increased expression of runt-related transcription factor-2/core binding factor alpha 1 (RUNX2/CBFA1), osterix, inhibitor of DNA binding/differentiation-1 (ID1), osteopontin, and bone sialoprotein genes, compared with rhBMP-2. Quantitative and qualitative differences in IL-2 and IL-4 expression in primary and secondary T cell stimulation. We found that cyclin B2 is detected from stage 2 to stage 6 as two bands, one of which is phosphorylated, and that cyclin B2 mass increases about 28-fold between stage 2 and stage 6.

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Intravenous bolus injection of rh-renin produced dose-dependent increases in MBP in pithed SHR and WKY. Northern analysis showed that Bt2-cAMP induced an increase in the five characteristic TGF-beta 2 transcripts and had no effect on the level of TGF-beta 1 or TGF-beta 3 transcripts. Human gingival keratinocytes were cultured and, after the first passage, subjected to cell detachment assays with polymorphonuclear leucocytes (PMNs) and/or sonic extracts from Actinobacillus actinomycetemcomitans Y4, and Eikenella corrodens 1073. Isolation of secretory IgA from feline bile and bile IgA levels in growing cats. We describe a workflow for successfully freezing, sectioning and staining tissue for laser microdissection.

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Synthetic peptide antisera: their production and use in the cloning of matrix proteins. The replica provides an accurate and permanent record of the shape and dimensions of the base of the cranial cavity, together with the location and extent of any fractures of the skull.

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Twelve sets of incisors of Cape mountain zebras, 9 of which were from known-age individuals ranging in age from 11 months to 19 years, from the Mountain Zebra National Park, are described and depicted to illustrate not only the eruption and replacement sequence, but also the changes with increasing age in the configuration of the occlusal surfaces and of the infudibulum. Increases in heart rate that exceed the exercise ischemic threshold are commonly observed before the onset of episodes of ambulatory myocardial ischemia in patients with stable coronary artery disease.

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Emotion and Theory of Mind in Schizophrenia-Investigating the Role of the Cerebellum. We suggest that Chr directly affects heart performance, protects against I/R myocardial injuries through the activation of prosurvival kinases. New kind of accident from the use of hydrosoluble contrast media in bronchography Detection of a vigorous HIV-1-specific cytotoxic T lymphocyte response in cerebrospinal fluid from infected persons with AIDS dementia complex.

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No deep-seated infection was evident suggesting that the superficial lesions were exogenous in origin. HbA1c and Lower Extremity Amputation Risk in Patients With Diabetes: A Meta-Analysis. Of these patients, 224 were stage 3 patients who had undergone R0 resections. Examination of the time-course of permeability response revealed a biphasic pattern.

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Synchronous demodulation was used to enhance signal-to-noise ratio and allow operation under ambient lighting conditions. While baseline levels of IMCL concentration have been shown to be mainly dependent on the metabolic status (insulin sensitivity), on the level of training and on fibre composition in the muscles, studies applying different physical activity protocols revealed the dynamic of their depletion and replenishment. To evaluate podotrochlear bursa (navicular bursa) endoscopy as a diagnostic technique in horses and to correlate observations to radiographic and pathologic findings. ESTIMATES OF THE CONCENTRATIONS OF STRONTIUM-89, STRONTIUM-90, AND CESIUM-137 IN MILK AS A FUNCTION OF TIME AFTER AN ACUTE LOCALIZED CONTAMINATING EVENT.

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Genetic profile of Mycobacterium tuberculosis and treatment outcomes in human pulmonary tuberculosis in Tanzania. The 5-HT4 receptor partial agonist, renzapride (3, 10, 30, 100 and 300 micrograms.kg-1), also increased heart rate and LVdP/dtmax dose-dependently.

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Values of Hill coefficient were below 1 in the hormone-protein interactions, which appears to occur due to polymerization of the protein or to appearance of unknown factors(s) in blood of old animals. However, evaluation of toe pinch force might be recommended for assessment of distal limb muscle strength in patients with type 2 diabetes. Spiro-fused carbohydrate oxazoline ligands: Synthesis and application as enantio-discrimination agents in asymmetric allylic alkylation. A role for a member of the inter-alpha-trypsin inhibitor family.

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Water treatment processes removed the two largest fractions almost completely shifting the MSD towards smaller molecular size in DW. Enhanced level of TNF-alpha is related to a higher cytotoxic activity. Watchful observation was applied to him, while strenuous physical activity and competitive sport were absolutely prohibited. Exchange transfusion as preparation of patient for surgery in chronic anemia To describe the cause and nature of injuries, and care-seeking behaviour following injury, among community-dwelling older adults.

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The calibration of the each device was begun when the BIS dropped to 60. The author emphasizes early provision of outreach help that includes both parents and any children in the family.

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The implications of the model concerning the debate on the locus of selective attention as well as the origins of distractor interference in visual displays of varying load are discussed. Short-term exposure to insulin-like growth factors stimulates testosterone production by testicular interstitial cells. Under the assumptions that the guinea pig lineage and the myomorph (mouse, rat, and hamster) lineage diverged 70-100 million years (Myr) ago and that the rate of nucleotide substitution has been constant in all these lineages since their divergence, the date of the mouse-rat split is estimated to be between 20 and 29 Myr ago, which is considerably older than the date (approximately 12 Myr) suggested by available rodent fossils and considerably younger than the date (approximately 35 Myr) suggested by Wilson and colleagues.

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(2) Extensive lymph node dissection should be performed for ESCC with poor differentiation and deep tumor invasion. A modification in the composition of isolation media promotes the growth of type F38 mycoplasmas and inhibits the growth of M. Therefore, the aim of this study was to investigate the influence of major virulence factors of P.

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Increase in sister chromatid exchange rates in association with occupational exposure to N,N-dimethylformamide. After day 10 of transient occlusion, we evaluated the effect of ASA and hUCMs on the recovery of learning and memory in rats by Morris water maze. Intravesical red light (630 nm) from an argon dye laser was used to activate the photosensitiser, using light doses of 12 or 24 J/cm2. Lesioning the insular cortex did not affect mean blood pressure or the heart rate.

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NADPH oxidase is upregulated in smooth muscle cells (SMCs) in response to growth factor stimulation, concomitant with increased reactive oxygen species (ROS) production. Effect of diabetes education on self-care, metabolic control, and emotional well-being. A multifunctional gold nanorod (AuNR) complex is described with potential utility for theranostic anticancer treatment.

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Implications for procedures to measure prostate specific antigen in serum. Human zona pellucida during in vitro fertilization: an ultrastructural study using saponin, ruthenium red, and osmium-thiocarbohydrazide. EST and EPBD can be safely performed in patients receiving antiplatelet agents. Most mononuclear leukocytes and cell lines express the integrin alpha 4 beta 1 (VLA-4) heterodimer.

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Morphological studies of formation of coated pits and coated vesicles in broken cells. Impact of Noncommunicable Disease Multimorbidity on Healthcare Utilisation and Out-Of-Pocket Expenditures in Middle-Income Countries: Cross Sectional Analysis. Triglyceride hydrolysis by cytosolic and lysosomal lipases mobilizes fatty acids from lipid droplet stores.

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Identification of metabolites of ampicillin using liquid chromatography/thermospray mass spectrometry and fast atom bombardment tandem mass spectrometry. xylosus occurred preferentially through epidermal growth factor TPK activity.

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The antimicrobial preservation systems were less effective against P. Resistance of Cercospora species to the toxic effects of their own toxin has allowed these organisms to be used as a model for understanding the cellular basis of resistance to singlet oxygen and to general oxidative stress. A Case of Perimembranous Ventricular Septal Defect Associated with Sinus of Valsalva Aneurysm Mimicking Membranous Septal Aneurysm.

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The ability of rabbit deep flexor tendons to restore the gliding surface and to heal, without the normal contribution of the superficial epitenon layer of the tendons, was studied by light and scanning electron microscopy. A further aim was to investigate the correlation between individual personal UVR dosimeter reading and self-reported data in a diary about sun exposure habits and to investigate whether skin type, age and gender influence sun exposure.

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Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis. Thus, the results of this double-blind clinical study, conducted according to a protocol which had been approved by the Council on Scientific Affairs of the American Dental Association, support the conclusion that Colgate Total Plus Whitening Toothpaste and Colgate Total Toothpaste provide effective control of breath odor at twelve hours after toothbrushing. A cadaveric porcine spine motion segment experiment was conducted. Dynamic construction of the neural networks underpinning empathy for pain.

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Controlled Allergen Challenge Facilities and Their Unique Contributions to Allergic Rhinitis Research. Such aspects need to be considered to plan specific prevention policies. Such subjects have been classified according to the hormone-binding characteristics in genital skin fibroblasts and on the basis of the mutation in the androgen receptor (AR) gene.

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Meiotic human sperm cells express a leucine-rich homologue of Caenorhabditis elegans early embryogenesis gene, Zyg-11. It is concluded that the decreased total energy retentions caused by single deficiencies of lysine and SAA were associated with decreased food intake. Observation noise is added when the state variables are observed. The developmental profile of a child with autism during the first 3 years of life is presented.

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Furthermore, comparisons with simulations and previous results obtained using standard calibration hint that both the quality of recorded signals and the performance of the system were comparable to those obtained with a standard calibration approach. From the catalog, we reliably identified 3172 proteins and 9,865,230 tags mapped to genes, and subsets of 141 proteins and 98 mRNAs, which were differentially expressed between the dl2 mutant and wild type. These results suggest that lead nitrate affects the lipid metabolism of the fish and this may reduce the fecundity of the fish since lipids are known to play an important role in teleost reproduction as an energy source and a precursor of steroids. Flotation experiments with membranes of BDV-infected cells on density gradients revealed that p16 is not an integral membrane protein, since it can be dissociated from membranes.

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EFFECT OF VARIOUS FUNCTIONAL CONDITIONS OF THE CENTRAL NERVOUS SYSTEM ON RESPIRATION AND OXIDATIVE PHOSPHORYLATION OF THE BRAIN TISSUE IN ACUTE CLOSED CEREBROCRANIAL INJURY To gain insights into the biological expression of matrilysin in human cell types, we generated a monospecific, polyclonal antibody against a 16-amino acid sequence derived from its catalytic domain, a region which lacked significant homology with other matrix metalloenzymes.

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The relationship of support, availability, and attitude to research utilization. The data are consistent with the formation of an 80 kDa urokinase-inhibitor complex in the presence of heparan sulfate proteoglycan and a 68 kDa complex in the absence of heparan sulfate proteoglycan. We demonstrate, for the first time, in airway epithelial cells in vitro that nDEP induce the expression of the CYP1A1, a cytochrome P450 specifically involved in polycyclic aromatic hydrocarbons metabolism, thereby demonstrating the critical role of organic compounds in the DEP-induced proinflammatory response. The NHIC is unique in that it is managed by the Department of Nursing and serves as a site for implementing the clinical objectives of the nursing programme. The diagnostic accuracy of OSNA for NAC-treated patients is similar to that for NAC-nontreated patients, but its accuracy is significantly lower for SLNs than for non-SLNs.

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The revised CD-RISC with a Chinese military sample provides insight into the resilience measurement framework and could be a reliable and valid measurement for evaluating resilience in a Chinese military population. Pharmacologic treatment for postviral olfactory dysfunction: a systematic review. The cost-effectiveness of photodynamic therapy for fellow eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. Both are alive and well 1 year after treatment, the longest recorded infant survival. Common textile manufacturing techniques, such as weaving, knitting, braiding, and electrospinning, are frequently used to design vascular implants for research and commercial purposes for the past decades.