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Molecular basis for the synergistic interaction of adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9). A case of amniotic band syndrome with bilateral epibulbar choristoma.

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We have prepared karyotypes from a malignant fibrous histiocytoma (MFH) of the brain of a 6-year-old girl. Patients with refractory patch/plaque disease were randomized to a high-dose (300 mg/m(2)) or low-dose (6.5 mg/m(2)) daily oral regimen of bexarotene.

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Their symptoms are diverse and correlate poorly with the objective abnormalities of gastric emptying. Pb(II) ion was removed mainly through the chemical reaction, while the uptake of Zn(II) ion onto crab shell was attributed to the chelation and coordination interactions.

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This operation always made these hips painless, 5 times, the mobility was greatly improved. To identify the routes by which oculomotor vermis signals control eye movements (saccadic signals), saccades evoked by microstimulation were studied in the region of the uncinate fasciculus (UF) and juxtarestiform body (JB) in the macaque monkey.

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All cases were treated with nonsurgical measures, such as metallic clips, conservative treatment alone and therapeutic drainage. Transfusion management of patients with IgA deficiency and anti-IgA during liver transplantation. Grafted neostriatal neurons express a late-developing transient potassium current. L 1210-MAF cells, obtained by treatment of L 1210 cells two times with 50 micrograms/ml or 100 micrograms/ml of Mafosfamide, and injected into the mice induced resistance against L 1210 leukemia in these animals.

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Task-Dependent Bimanual Coordination After Stroke: Relationship With Sensorimotor Impairments. However, it remains difficult to classify a number of such lesions. Specifically the controversies in familial adenomatous polyposis include the timing and the type of surgery while for Lynch syndrome discussion revolves about prophylactic surgery, primary, secondary and tertiary. Diabetes in Canada: direct medical costs of major macrovascular complications.

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To ascertain the frequency with which paramedics follow protocols for the administration of aspirin to patients to whom an ambulance is called for chest pain associated with suspected ischaemic heart disease. Outcomes of pancreaticoduodenectomy in patients with metastatic cancer.

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All three estrogen nitrosourea conjugates were more cytotoxic than CCNU, a clinically useful antitumor nitrosourea which does not bind to ER. Time-series regression analysis and episode analysis of daily mortality, emergency hospital admissions, and accident and emergency visits for each region of England. Polymyxin B (a protein kinase C inhibitor) mimics the actions of 5-HT on fluid reabsorption and on calcium-dependent cAMP accumulation.

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Scintigraphic assessment of patients with pulmonary thromboembolism by extent of perfusion defect and right ventricular function The present review considers ongoing translational research efforts on clinicopathological, molecular biological, and genetic prognostic and/or predictive factors for metastatic renal cell carcinoma patients in the era of molecular-targeted therapy, and discusses the clinical implications of these findings. Comparison of 30mCi and higher doses of iodine-131 for postoperative thyroid remnant ablation The importance of gadolinium-diethylenetriamine-penta-acetic acid (Gd-DTPA) in MRI for delineation, and differential diagnosis of the inflammatory processes has been considered.

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EFFECTIVENESS OF ANTIBACTERIAL THERAPY OF PATIENTS WITH PULMONARY TUBERCULOSIS AND ASBESTOSIS EMPLOYED IN THE ASBESTOS INDUSTRY In an attempt to find factors that may be responsible for the initiation of sporulation, a system in which the germination and outgrowth phases were separate was applied to Bacillus subtilis. The mechanisms involved are T-cell-mediated destruction of infected cells and delayed-type hypersensitivity. Both amygdala and ACC volume and function are affected in bipolar disorder, with the ACC showing phase-dependent resting state activity differences. Tall cell variant of papillary breast carcinoma: report of a case

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Effect of dose, pH, and osmolarity on nasal absorption of secretin in rats. Status of the monooxygenase enzyme system in rat and rabbit organs in sugar diabetes and upon insulin administration Effect of prodectin on the activity of the blood kallikrein-kinin system in diffuse toxic goiter Remarkably, their biochemical content includes not only lipids and proteins, but also nucleic acids, mainly miRNA and mRNA, with a few reports also indicating the presence of genomic and mitochondrial DNA. The presence of AMPs throughout evolution hints at their importance.

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PREPARATION OF MICROSCOPICAL SLIDES TO SIMPLIFY IMMUNOFLUORESCENCE SEROLOGICAL TITRATIONS. No effects of MXC on ovarian weight, serum progesterone levels, or number of corpora lutea were observed. The basic level was in the range 1-25 ng/ml for lipoic acid and 33-145 ng/ml for dihydrolipoic acid (6 healthy volunteers). Before the intervention, families reported goals to increase physical activity, plan and eat healthier meals, reduce screen time, and lose weight.

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In tumour microenvironments, their presence is related to a poor prognosis, and they influence the therapeutic outcome due to their capacity to suppress the immune response by cell-cell contact and to release immunosuppressive cytokines. COMPARATIVE STUDY OF METHODS OF PREPARATION OF HUMAN HAPTOGLOBINS The results suggested that the 64 slice spiral CT could be a valuable and accurate method for measuring the length of optics canal walls. Retroperitoneal malignant lymphoma showing follicular type: report of a case

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More than 20 years ago, Warren and Zeppa introduced the concept of selective shunting to prevent recurrent variceal hemorrhage. Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer.

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Man, GlcNAc, Gal residues and complex sugars were also noted in the stromal tissues of the lateral prostate including the extracellular matrix, capillaries and smooth muscle. Prediction of T cell epitopes of Brucella abortus and evaluation of their protective role in mice.

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PATHOPHYSIOLOGY OF THE LIVER AND PANCREAS IN EXPERIMENTALLY PRODUCED ACUTE PANCREATIC NECROSIS AND THERAPEUTIC EFFECT OF PENICILLIN. We have begun a systematic study of growth factors and their relationship to this specific pattern of growth retardation.

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Effects of guanabenz acetate on the pacemaker activity of rabbit sinoatrial node cells. ON THE NATURE OF THE CHANGES IN BODY COMPOSITION OF OBESE SUBJECTS DURING FASTING

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After 1, 3, 5, 7 and 10 week of training, five rats from every group were anesthetized and immunohistochemistry, Western blot, and PCR analyses were performed on obtained muscle tissue to determine VEGF-A expression. We previously investigated the functional neuroanatomy of familial pure depressive disease (FPDD) using positron emission tomography (PET) measurements of regional blood flow and obtained evidence that flow is increased in the left prefrontal cortex, amygdala, and medial thalamus and is decreased in the medial caudate. The remaining 6 samples were negative for the presence of SLE virus as determined by both methods. Clinical and radiologic examinations did not show an alternative primary site.

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Chemicals that interfere with dye/protein interactions in solution can be removed by washing the nitrocellulose after protein application. Three patients with unilateral palsy died of non-respiratory causes. Moreover, a good agreement between MRI-measured MSE, CT, and histology data quantitatively supports the presence of ventilation deficit in emphysematous lungs.In this work, we have demonstrated the feasibility of ventilation-related maps from non-contrast-enhanced H lung MRI, which were capable of tracking changes in lung function over time in emphysematous rats.

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In an effort to assess the level of phosphorylation of the transcriptionally active form of RNA polymerase II in HeLa nuclei, transcription was carried out in the presence of 4-thiouracil triphosphate and the nascent labeled transcript cross-linked to RNA polymerase. Lens protein composition, glycation and high molecular weight aggregation in aging rats. The number of microvilli per square micrometer of luminal epithelial surface area decreased with increased flow rate from a control value of 42.5 to 35.5 at high flow.

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The proper handling and disposal of Bio-medical waste (BMW) is very imperative. No histopathology was observed following the introduction of plasmids encoding several different gene products, and analysis of serum following DNA liposome delivery revealed no abnormalities of serum biochemical parameters. Analysis of the fatty acids in the erythrocyte lipid of multiple sclerosis patients in Italy gave no indication of any difference in composition compared with that of a healthy control group. These clones were used to determine the amino acid sequences that encompass the epitopes of five anti-MYHC monoclonal antibodies. Therapeutic alternatives for hormone-refractory prostatic cancer.

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Doses of 500 rad and 1 k rad resulted in hypoactivity of thyroid but could not affect adrenal and pancreatic islets. The treatment consisted of UK (4500 IU/kg/hr for 12 hours) or SK (2,000,000 IU over 10 hours). PHOTOCHEMICAL REACTIONS OF NUCLEIC ACID COMPONENTS IN FROZEN SOLUTIONS. These findings indicate that thymic tolerance specific for tissue can be stimulated to occur in the presence of atopic tissue-specific intrathymic antigens.

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Honey bee (Apis mellifera) drones and workers show differences in morphology, physiology, and behavior. The sociology of childbirth: an autobiographical journey through four decades of research. The interruption of amiodarone improved the neurological symptoms.

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The consistency of the results among the various biological systems and endpoints led to the conclusion that the consumption of chlorinated drinking water obtained from polluted raw water may enhance the body burden with mutagenic and/or carcinogenic substances and therefore, means a potential genetic hazard for human health. In younger patients more discomfort is associated with this procedure. Gross abnormalities of kidney in congenital osteochondrodysplasia rat (ocd/ocd). Vaginal biocenosis in pregnancy and local therapy of vaginitis in pregnancy Potential influences of ketoprofen on human healthy and osteoarthritic cartilage in vitro.

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All the bacteria isolated have the ability to stimulate the infiltration of round cells into the dermis, which is the essential feature of the pathological changes in the naturally affected skin. The influence of central arterial compliance on cerebrovascular hemodynamics: insights from endurance training intervention. The present study focused on 4 patients with ICoVT, 2 men and 2 women. Although operative mortality for repair of atrioventricular septal defect has decreased dramatically during the past decade, the incidence of late reoperation for mitral regurgitation has not improved, and better techniques to eliminate late mitral regurgitation are needed. Future studies should focus on distinguishing which patient populations, if any, would optimally benefit from intensive insulin therapy.

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These results do not indicate any trend suggesting that Def, as a prophylactic agent in gynaecological surgery, offers any clinical or practical advantages over standard low-dose heparin prophylaxis. The aim of this study was to investigate the correlation between autonomic dysfunction in multiple sclerosis (MS) and brainstem dysfunction evaluated with the vestibular evoked myogenic potentials (VEMP) score and conventional MRI.

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We performed a meta-analysis of randomized controlled trials (RCTs) to investigate the efficacy and safety of tolvaptan in the treatment of patients hospitalized for heart failure (HF). We performed a 4-year retrospective review of patients undergoing abdominal wall hernia repair, with and without TISSEEL, by a single surgeon (FEE) at The Johns Hopkins Hospital.

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Corneal stromal lamellae orientation can be efficiently assessed and displayed as a cross-like image by the polarimetric interferometer. On the other hand, relationship between neurological involvement and metabolic disorder is still obscure. However, growth of RSV and RAV was inhibited by both the tissue culture-grown and the agar-grown 941 strain, and also by the CH19299 strain which did not produce any cytopathic effect. This review is mainly focused on the recent structure-function studies of the earliest known temporin isoforms (TA, TB and TL) and their potential clinical role as novel antimicrobial agents.

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Evaluation of the interaction of peptides with Cu(II), Ni(II), and Zn(II) by high-performance immobilized metal ion affinity chromatography. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma.

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The optimal duration of anticoagulation after a first episode of unprovoked pulmonary embolism is uncertain. Childhood maltreatment and unfavourable clinical outcomes in bipolar disorder: a systematic review and meta-analysis. The recombinant plasmid was restriction enzyme-digested and sequenced, and using liposome vectors, was transiently transfected into Free-Style 293-F cells (serum-free medium). The itch response to the neuropeptides and histamine was not different in atopics and controls. The PCR primer sets for each virus were designed and shown to be highly specific (did not amplify any recognised non-target template) and sensitive (detection of minimal amounts of virus) and, where multiple virus isolates were available all isolates were detected.

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However, the absence of extracellular calcium had no significant effect on the induction of cyclic AMP production by forskolin in pineals collected either early in the dark period or late in the dark phase. Reduced expression of HLA class I molecules has been demonstrated for many human neoplasias and is correlated with increased malignancy.

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Furthermore, when aligning motion to an external line, the errors depended on orientation of the line in addition to trunk and neck orientations, but not when aligning to intrinsic axes or earth-fixed vertical in the presence of an external line. It produced less myelosuppression, but more commonly produced hemorrhagic cystitis as its dose-limiting toxicity.

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An engineered fusion protein lacking most of the transit peptide, which was produced in Escherichia coli, was isolated and proved to possess beta-ketoacyl-ACP reductase activity. Finally, transcriptomic data showed that the enhanced bioconversion into acetate esters by the evolved strain was associated with the repression of genes involved in sterol biosynthesis rather than an enhanced expression of ATF1 and ATF2 (genes coding for the enzymes responsible for the synthesis of acetate esters from higher alcohols). Use of a replica-plate assay for the rapid assessment of salivary protein-bacteria interactions. There were no operative deaths while complications after a third hepatectomy contributed to a high morbidity rate of 40 per cent. These derivatives were tested for alpha-glucosidase inhibitory activity on rat small intestinal glycosidases.

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Evidence about the patterns of occurrence of cardio-metabolic markers and their interlinkage in the sub-Saharan African setting is inadequate. The objective of this study is to determine how dominant these two factors are in influencing the shape and power of MRPs.

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One way of addressing the remaining questions is by making use of computational models. With increasing longevity and a similar or increased prevalence of cardiovascular disease risk factors (as compared to the general population), people with intellectual disabilities (IDs) are at risk of developing cardiovascular disease. Angiogenin is a potent positive mediator of neovascularization, a process required for both primary tumor growth and metastasis. Ultra-high-performance liquid chromatography-mass spectrometry-based metabolomics analyses were performed to screen plasma metabolic profiles upon shock and resuscitation with either platelet-free plasma or normal saline in a rat model of severe hemorrhage.

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Removal of the catheter is rarely associated with occurrence of life-threatening complication such as serious liver damage. The molecular fingerprints were compared both to each other and to the larger repository of strains from New York City developed and maintained at the Public Health Research Institute.

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Cell cycle-dependent expression and nucleolar localization of hCAP-H. A new NMR experiment for correlating diffusion coefficients and chemical shifts is presented.