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In terms of natural amino-acid substrates, the triple mutant represents effective conversion of a glutamate dehydrogenase into a methionine dehydrogenase. The velocity, attenuation and frequency content of the mechanical pulse wave propagation in gels of various water contents, in normal tissues from various sites and in oedematous tissues from different patients were investigated. Intramuscular pressures during exercise: an evaluation of a fiber optic transducer-tipped catheter system.

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Increased magnesium was detected in the enamel at the late developmental stage, and a delay in enamel mineralization resulted from increased magnesium uptake. The foundation upon which surgical residents are trained to work comprises more than just critical cognitive, clinical, and technical skill.

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DYNA CT has substantial advantages over routine DSA in demonstrating the shape and branches of the target hepatic vessels and the number of tumors. Six months after the first operation she underwent a corrective re-operation for release from the PVO using EPTFE (expanded polytetrafluoroethylene) patch. This concept has been tested in the rabbit ear model in which an injection of papain into the rabbit causes loss of proteoglycans of the auricular matrix followed by its restoration over the following eight days.

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The effects of glare on contrast sensitivity and high contrast Snellen acuity were investigated in a group of unilaterally aphakic patients with normal fellow eyes. Dorsal premotor activity and connectivity relate to action selection performance after stroke. Seven premature infants with hypozincemia and transient symptomatic zinc deficiency have been previously described.

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ON THE END ACTIVATOR, A BIOLOGICALLY ACTIVE OXIDATION PRODUCT OF ERGOSTEROLS, SPECIFICALLY 7-DEHYDROCHOLESTEROL. Frequency and determinants of Hepatitis B and C virus in general population of Farash Town, Islamabad. The D-amino acid transport by the invertebrate SLC6 transporters KAAT1 and CAATCH1 from Manduca sexta. These can all result in induced pain which can be prevented thanks to the knowledge and skills of the caregivers along with pharmacological and non-pharmacological treatments. Attention is called to the similarity of this symptom complex to that observed in AIDS.

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The development of amoebiasis is influenced by the expression of the lysine and glutamic acid rich protein 1 (KERP1), a virulence factor involved in Entamoeba histolytica adherence to human cells. An analytical equation of state for describing isotropic-nematic phase equilibria of Lennard-Jones chain fluids with variable degree of molecular flexibility.

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To study whether weekly low dose of mifepristone (5 mg or 10 mg) is sufficient to prevent pregnancy. We found no evidence for chondrocyte hypertrophy within hyaline cartilage of AS joints even in the presence of reduced expression of the wnt inhibitor wif-1 suggesting that chondrocyte hypertrophy is not a predominant pathway involved in joint fusion and remodeling in AS. She had received right mastectomy for breast cancer under general anesthesia 6 days before the admission. Complete medium from melanoma cell cultures stimulated fibroblast hyaluronate synthesis 9.3-fold, and sulphated GAG synthesis 2.6-fold, as measured by 3H-glucosamine incorporation.

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Structure from stereo by associative learning of the constraints. Regulation of mammary glucose uptake in goats: role of mammary gland supply, insulin, IGF-1 and synthetic capacity. Reclassification and split-half classification showed a high overlap between LCA5 and automatic classification. To address the effect of bimatoprost on the mechanosensitive TG nerve endings in the inner walls of rat anterior chambers, we investigated its effect on their cell bodies in vitro.

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A cross-sectional survey was carried out in 24 LBMs at the beginning of H7N9 outbreak in all affected provinces. No positive correlations was found between the rhythmic changes in heat resistance and the rhythmic changes in the synthesis of any HSP. The technique was found to produce quantitative agreement with a clinical diagnosis of lymphoedema and with the currently-used measure (limb volume calculated from circumferential measurements) of limb size. In this study, we investigated the expression of various G proteins in whole sciatic nerves, in myelin and nonmyelin fractions from these nerves, and in membranes of immortalized Schwann cells. Only the highest dose of extracts (160 mg/kg) attenuated intensity of harmaline-induced tremors throughout the study.

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The studies described in this report were performed to characterize phospholipase C isoform expression at the protein level and to confirm histologic localization of these proteins within the myometrial smooth muscle layers of the uterus. Sorption of weak organic acids in soils: clofencet, 2,4-D and salicylic acid.

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No differences have resulted in terms of anatomic relationship between males and females apart from a higher risk of real contact without corticalization of the canal when the IAN had a lingual course for female group. Adult neurogenesis and neurodegenerative diseases: A systems biology perspective.

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Trauma to the spinal cord induces a series of electrophysiological, immunological and biochemical events, but it is still unclear how such reactions are initiated and maintained. americana contains polymorphic AANAT, as is the case in Drosophila melanogaster. Most are duplicated or partially duplicated ACoAs that are confused with fenestration of the ACoA. Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages.

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Expression of phosphatidylinositol-dependent phospholipase C sensitive Qa-2 antigen is increased on peripheral blood lymphocytes of aging mice. ON THE EFFECT OF ACUTE VOLUME CHANGES IN THE ABDOMEN ON THE INTRA-ABDOMINAL PRESSURE AND VENOUS REFLUX In addition, NAT10 promotes Mdm2 degradation with its intrinsic E3 ligase activity. In this case report, we report what we believe to be the first case of imatinib mesylate or STI-571 (Novartis) use for treatment of idiopathic hypereosinophilia syndrome (HES).

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Wild relatives of barley possess attractive properties and hence allelic diversity for adapting barley better to changing environmental conditions. COX-2 inhibitors might be valuable drugs to treat salt and water wasting during Bartter and Gitelman diseases. This is particularly critical within the thorax, where many spindle cell neoplasms represent tumours of epithelial origin or metastatic disease. Cochlear sections were incubated with a monoclonal antibody raised against HSP72 and relative staining densities were quantified with a light microscopic image analysis system.

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The enhanced tolerability and superior efficacy of anti-aromatase inhibitors compared with megestrol acetate has resulted in these agents becoming the endocrine treatment of choice for women with advanced breast cancer who have progressed after tamoxifen treatment. Anisotropy is the property of tendons, nerves and muscles to vary in their ultrasound appearance depending on the angle of insonation of the incident ultrasound beam.

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The serine proteinases of human neutrophils were analyzed with Elastase-substrates such as (Z-Ala-Ala)2-R110 or (Z-Ala-Ala-Ala)2-R110. Studies on circadian periodicity of plasma 17-hydroxycorticosteroids (17-OHCS) in tropical pulmonary eosinophilia. To explore the inhibitory effect of sera from patients with myelodysplastic syndromes (MDS) on the growth of normal hematopoietic progenitor cells.

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Contribution of diabetes duration before puberty to development of microvascular complications in IDDM subjects. During delivery of DC anodal currents (100 microA) bilaterally to both ears, the slow phase eye velocity of the steady-state nystagmus during OVAR was reduced or completely abolished. The conservative technique of professionally dispensed and supervised, home-administered vital bleaching is now a routine treatment in the dental profession.

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Non-targeted chromatographic analyses of cuticular wax flavonoids from Physalis alkekengi L. By comparing metabolically labelled E/S from male and female worms, several molecules of low mol. Little is known regarding the incidence rate of and factors associated with developing chronic kidney disease after continuous renal replacement therapy (CRRT) in acute kidney injury (AKI) patients. Rate acceleration and long-branch attraction in a conserved gene of cryptic daphniid (Crustacea) species. Effects of CGS 10746B on hyperactivity and place preference induced by morphine.

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Evaluation of arthrography and arthroscopy for lesions of the posteromedial corner of the knee. A deglycosylated breakdown intermediate of the heavy chain identical to that generated in intact cells accumulates in soluble form in the presence of proteasome inhibitors. The association of anovulation and endometriosis in the infertile female. These data quantify the modest bradycardia associated with ophthalmic beta-blocker therapy in a typical patient population on therapy for glaucoma. Retrospective cross-sectional study conducted in a tertiary referral centre.

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Six distinct fractions were generally separated from water samples with the TSK G3000SW column, using sodium acetate at pH 7 as an eluent. In recent years, several laboratories have used recombinant DNA tools to determine, at the molecular level, the organization, expression, and regulation of genes involved in LPS biosynthesis in Salmonella and Escherichia coli. Antiuterotrophic effects of a pure antioestrogen, ICI 182,780: magnetic resonance imaging of the uterus in ovariectomized monkeys.

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CASE REPORT XII OF THE MATERNAL MORTALITY STUDY: RUPTURED UTERUS. Software, written in C language and running under the MS-DOS/MS-Windows environment, is controlled by means of a mouse-driven cursor.

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The ratio of SUV(max) is a valuable diagnostic method in detecting diffuse large B-cell lymphoatic bone marrow involvement. Results of a specific therapy of pollinosis by administration of pollen extracts

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Under CO2 atmosphere, p-toluic acid was transformed by the sediment microorganisms without a lag period, while under N2/H2 atmosphere, p-toluic acid was transformed after a lag period of 55 days. Nutrition likely influences social interactions in many species, and yet a theoretical framework for exploring these effects is currently lacking. The Drug Enforcement Administration is amending the table of Excluded Nonnarcotic Products to update the company name for the drug product Nasal Decongestant Inhaler/Vapor Inhaler (containing 50 milligrams levmetamfetamine) to Aphena Pharma Solutions--New York, LLC. We suggest that many instance of voice-hearing should be approached differently. Technological improvements both in digital photography and image analysis allow cheap and easy monitoring of circadian leaf movements.

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Measurement of oxidized guanine species and antioxidant enzymes in the sputum could be other approaches for assessing oxidative stress in pulmonary patients. These approaches can be useful in the development of a format for sharable CIGs. We synthesized data from clinical and animal studies in order to determine optimal AE training parameters and recovery outcomes for future research. Behavioral selection of odor cues by young female mice affects age of puberty. Pain is recognized as one of the major reasons for termination of the use of the IUD.

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Pilot study of dose dependence in glucuronidation of morphine to morphine-3- and morphine-5-glucuronide We hypothesized that these patches were a rare cutaneous finding in NF-1 that exist on a clinical and histopathologic spectrum with previously described NF-1 vascular lesions including blue-red macules and skin ulceration due to NF-1 vasculopathy. In particular, neuromuscular junctions (NMJs) are affected by dramatic alterations, including immaturity, denervation and neurofilament accumulation, associated to impaired synaptic functions: these abnormalities may in turn have a detrimental effect on MN survival. These antibodies are significantly more prevalent in asymptomatic carriers than in AIDS patients (1). The present study investigates filtration forces of monoclonal antibody formulations in a small-scale set-up using polyvinylidene difluoride (PVDF) or polyethersulfone (PES) filters.

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Molecular analysis of the glpFKX regions of Escherichia coli and Shigella flexneri. Analysis with our mathematical model revealed that T160 phosphorylation of CDK2 correlated best with growth factor-dependent proliferation, which we validated experimentally on both the population and the single cell level. The clinical traits of Kufs disease (KD) type B (CLN13), an adult-onset neuronal ceroid lipofuscinosis (NCL), are well established according to the neurological features of the cases reported with mutations in CTSF. Congenital functional obstruction of the mid ureter has only 17 reported cases, that too of unilateral pathology. The very early diagnosis of a fetal heart block in bradycardiac fetus by echocardiography is essential for a consecutive therapy with steroids.

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High temperatures and absence of light affect the hatching of resting eggs of Daphnia in the tropics. Kidney copper levels increased transitorily after 2 weeks but not after 4 weeks. Experiments were performed to evaluate the in vitro and in vivo dose response for antigenotoxic effects of resveratrol (RES). Although most prior mutations in the highly conserved boundary motif of the alpha-helix have resulted in the Dowling-Meara subtype, our findings confirm that it is not always possible to predict the epidermolysis bullosa simplex severity on the basis of the location of the mutation along the keratin polypeptide.

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A critical role for ATR has been hypothesized to be the regulation of p53 and other cell cycle checkpoints. In the practical application of this technique for the study of diabetic retinopathy, visual field scotomata were found corresponding to areas displaying signs of retinal vascular impairment in the form of vascular occlusion, while no relation was found between visual field scotomata and breakdown of the blood-retina barrier as studied on fluorescein angiograms. The present study was designed to determine whether there is a causal relationship between noise-induced hypertension and changes of endothelial function.

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This article is an evaluation of the consequences of letting medical students set some of their own exam papers. This study aimed to analyze whether undifferentiated mesenchymal stromal cells (U-MSCs) or MSC-derived hepatocyte-like cells (DHLCs) from adipose tissue (AT), umbilical cord blood (UCB) and bone marrow (BM) would better restore damaged liver. In this analysis, we estimate the impact of the changing relative size of the adult male population, classified by age and education groups, on the earnings of employed men living in 502 Brazilian local labor markets during four time periods between 1970 and 2000.

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It is shown that unspecificity of this protein can be explained only when taking into account flexibility of the base recognition loop. Marijuana has been used for a variety of medical purposes, including management of nausea and vomiting, appetite and immunologic stimulation in patients with HIV infection and AIDS, glaucoma, neurologic disorders, and pain relief. The regulatory effects of allelic substitution at the trans-acting mapP locus and of dietary glucose on the expression of the duplicate genes for alpha-amylase (Amy) in Drosophila melanogaster were examined in the anterior midgut and posterior midgut regions of mature flies. Placental transfer and tissue distribution of thiopental in the pregnant rat. The assay was applied to the evaluation of the effects of several antimalarial drugs on the enzyme.

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In a second series of experiments, the synaptic contacts between nigrotectal terminals and the tectospinal component of the predorsal bundle were examined in tissue in which both the terminals and the tectospinal cells were labeled for electron microscopy. Tumor-induced osteomalacia due to a recurrent mesenchymal tumor overexpressing several growth factor receptors. Relaxation of superhelical DNA by Escherichia coli topoisomerase III (Topo III) was inhibited by the inclusion of tRNA in the reaction mixture. A circle representing enface view of opacity divided into 100 equal parts is used in calculating the area of each opacity. Moreover, these compounds have activity in whole cells that reflect the potency and selectivity of target inhibition determined with this assay system.

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The melanin operon (melC) of Streptomyces antibioticus is composed of two genes that encode MelC1 and MelC2 proteins. These results suggest that psychometrically defined mental health phenotypes can reflect the dimensions of complex phenotypes better than summation scores, and therefore offer a useful approach in genetic association investigations. We have isolated an endoxy loglucan transferase (EXGT) gene that is strongly expressed in pea roots and appears to be involved in the differential growth in hydrotropically responding roots.