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Cyclophosphamide
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Cyclophosphamide

Cyclophosphamide is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Cyclophosphamide is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin). It belongs to the group of cancer medicines called alkylating agents.

Cyclophosphamide is also used for some kinds of kidney disease.

Cyclophosphamide interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by cyclophosphamide, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with cyclophosphamide, you and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule
  • Powder for Solution
  • Tablet

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Commodities sampled included peanuts and peanut products, tree nuts, corn and corn products, cottonseed, and milk. Demonstration of Golgi zones by three technics for carbohydrates. Unstimulated and phytohaemagglutinin-stimulated PBMCs were tested with and without the addition of AS101. In dafeng county of Jiangsu province, 710 healthy women, aged 22-32 years, were randomly allocated to use one of the title IUDs 3-9 months postpartum in a single-blind manner.

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We aimed to characterize the clinical and electrophysiological features of patients with slow orthostatic tremor. A retrospective review of cases at a level I pediatric trauma center from 1995 through 1999 was conducted to identify cases of suspected shaken baby syndrome.

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The differential diagnosis in patients with aortic dilation is broad and includes many conditions outside the common connective tissue disorder spectrum. Despite the great need, effective vaccines and practical antiviral therapies are still under development. Immunohistochemistry reveals that the fins are highly innervated, and we observe putative mechanoreceptors at nerve fibre endings. Should bone marrow transplantation be included in the primary therapy of patients with aggressive lymphoma? EXTRAHYPOPHYSEAL REGULATION OF ADRENAL STEROIDS AND ITS POSSIBLE PART IN STRESS REACTIONS OF THE ORGANISM

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The mechanisms involved in the generation of oxidative damage and lung inflammation induced by physical exercise are described. Although the Candida carriage rate and density were statistically higher in diabetics than healthy individuals, no direct association was found between having high Candida-burden and glycosylated hemoglobin. In situ hybridization of tissues from two horses infected with the wild-type Wyoming strain of equine infectious anemia virus (EIAV) identified the liver, spleen, lymph nodes, kidney, lung, and adrenal gland as the primary host tissue sites for viral transcription during acute infection.

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European Erythema migrans Borreliosis and North American Lyme disease are closely related to syphilis. Haploid, diploid, and mixoploid individuals were detected using flow cytometry, demonstrating that this technique was efficient for identifying doubled haploids. Maintaining ocular safety with light exposure, focusing on devices for optogenetic stimulation.

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TGF-beta 1, however, was unable to induce PKC enzymatic activity in cells pretreated with calphostin C. In this paper the pressure gravidiffusive model equation in a single-membrane osmotic-diffusive cell is elaborated. The appropriate model to explain the experimental design effects on such ratio standards was shown to be log-normal rather than normal.

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A possible application of the method to biologically significant DNA tracts is shown in the case of the regulative region of one of the genes which code for the small subunit of ribulose-1,5-bisphosphate carboxylase in Pisum sativum. We then identified additional constraints and the cellular objective function required to match experimental observations. Students received a face-to-face lecture, two webinars, used chat rooms and were asked to create course Twitter accounts and were assessed on their use.

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This paper highlights that prisoners perceive that the prison environment has a negative influence upon their mental health. Mice exposed to stochastic 24h starvation events altered their behaviour (reduced activity) during the refeeding days that followed the deprivation periods to regain the lost mass. The synthesis and antimicrobial activities against Gram-positive and Gram-negative bacteria of some 1-substituted quinolones related to pirfloxacin are reported. Alena is a nurse in Prague--she dreams of higher wages and a trip across the ocean

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Yet, somewhat paradoxically, for large capillaries relatively little resistance is within or in the immediate vicinity of the red cells. Ox-LDL-TLR2 pathway activation and further inflammation in monocytes are involved in the atherosclerosis formation.

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Normal insulin receptors in mitochondrial myopathies with ophthalmoplegia. Molecular diagnostics in low-grade gastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type after Helicobacter pylori eradication therapy. We show here that one gene, nodC, shows striking similarity to genes encoding proteins known to be involved in polysaccharide synthesis in yeast and bacteria, specifically chitin and cellulose synthases, as well as a protein with unknown function in Xenopus embryos, DG42. In recent years cases of anaphylaxis, rhinitis, and asthma due to latex have appeared. 11 beta-hydroxylase activities of the single CYP11B gene in sheep.

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Improved results of reconstruction operations were achieved for operation by suture compared to operations by nerve graft. An update is given of the known interrelation between lipids and immunity, with appraisal of triglycerides and long-medium -- and short-chain fatty acids, mixtures of medium -- and long-chain triglycerides, the proportions between infinity-3/infinity-6, and structured lipids. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. The humerus between the host and grafted polarizing region was largely normal though there were variations in width, particularly the distal epiphysis.

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coli PNA probe, as expected from sequence data, also detected Shigella species. During the twentieth century disease detectives progressed by jagged leaps in understanding patterns of plant disease. By using radioimmunoassay, immunoprecipitation and Western blotting techniques we demonstrate for the first time that type II cells, isolated from mature rabbit lungs, synthesize and secrete UG.

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Godlewski has drawn attention to the sex ratio of transsexuals requesting sexological treatment in Poland. Further follow-up and experience is warranted before conclusions regarding potential benefits of this approach for staged or conventional OPCAB/CEA procedures can be made.

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Brachioradial pruritus is a chronic sensory neuropathy of unknown etiology which affects the skin of the shoulders, arms and forearms on the insertion of the brachioradialis muscle. Surgical endoprostheses might be an alternative in cases with peroperative loss of substance of the common bile duct in patients with neoplastic disease to hepato-enteric anastomoses. Subcostal lower pole nephropexy to facilitate removal of calculi of the recurrent type. A multicenter study of using carbon nanoparticles to show sentinel lymph nodes in early gastric cancer. Identification of envelope protein epitopes that are important in the attenuation process of wild-type yellow fever virus.

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Moreover, longitudinal bone growth and the growth of epiphyseal width were reduced during early-age feed restriction, in both chickens and turkeys. Excision of the maxillary mass led both histopathological confirmation of the disease and early masticator rehabilitation. Identification of Pim-1 and SLP-76 as regulated by IL-5 led us to suggest a direct role for these proteins in the IL-5 signaling pathway in eosinophils.

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A transient increase in ROS production was induced in normal but not in SSc fibroblasts by interleukin-1beta (IL-1beta), platelet-derived growth factor type BB (PDGF-BB), transforming growth factor beta1 (TGFbeta1), and H2O2. EVALUATIONAL REACTIONS OF JEWISH AND ARAB ADOLESCENTS TO DIALECT AND LANGUAGE VARIATIONS.

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At the IC50 of azosemide and ethacrynic acid, the Kd values were significantly increased, while the Bmax values remained unchanged. Countering a multi-faceted terrorist wave through an integrated emergency-care system. RxT is unable to cure acromegaly, because it seldom achieves hormonal normalization even after a very prolonged follow-up. GPVI receptor density on human platelets appears tightly regulated, is independent from the level of alpha2beta1 expression, and significantly exceeds that on previously characterized GPVI-expressing RBL-2H3 cells. Studies on risk factors have not necessarily accurately demonstrated the risk factors of this disease because they were not prospective cohort studies or the populations in the studies were not categorized by the skeletal maturation of the tibial tuberosity.

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To validate the findings of a prior single-surgeon series with a multi-institutional comparison of three-dimensional imaging of volume preservation (3DVP) and surgeon assessment of volume preservation (SAVP) as predictors of renal function after partial nephrectomy (PN). These changes were most apparent in the rapid spread of the disease, the gross pathology of the footpad and in the rate at which the mice had to be euthanatized for ethical reasons. Interestingly, when FasL activity was inhibited in IC tumors, the proportion of tumor-infiltrating leukocytes increased three-fold, reaching the same frequency as the SC tumors.

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Keratins 1 (K1) and 10 (K10) are commonly expressed in the differentiating layer of benign tumors, but are lost during progression from the benign to the malignant state in skin carcinogenesis. Thus, clinical risk management (CRM) system has been introduced for improving the quality and safety of services to health care. Such a large availability has made possible to either carry out deeper investigations on the physiopathology of the hemopoietic regulation and perform new therapeutic approaches under different pathologic conditions. Paediatric and adolescent oral HIV research needs to be prioritized as current studies are few and are characterized by poor quality study designs, small study samples and a lack of multicentre collaborations.

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Regulation of progesterone secretion in human syncytiotrophoblast in culture by human chorionic gonadotropin. Acute intermittent porphyria is an inherited metabolic disorder which may remain undiagnosed throughout life unless appropriate biochemical analysis is being performed during an acute attack. Whether pituitary GH release is under the control of ghrelin from the stomach and/or from the arcuate nucleus is not known. High-quality epidemiological studies evaluating the burden of cutaneous leishmaniasis worldwide are lacking. A role for hypersensitivity responses was not confirmed by the weal responses but was suggested by the size of wound developed per larva recovered.

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Because of an abnormal echogram, he was submitted to exploratory cardiotomy and small ASD, aneurysmatic dilation of Valsalva sinus and mitral regurgitation by ruptured chordae tendineae were found. Does Moral Distress Differ Between California Certified Registered Nurse Anesthetists in Independent Versus Medically Supervised Practice: An Exploratory Study. The objectives of this study were to determine the dissolved CO2 and O2 concentrations in the purge of vacuum-packaged pork chops over a 60 day storage period, and to elucidate the relationship of dissolved CO2 and O2 to the microbial populations and shelf life. Ataxia-Telangiectasia and RAD3-Related and Ataxia-Telangiectasia-Mutated Proteins in Epithelial Ovarian Carcinoma: Their Expression and Clinical Significance.

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Clinical symptoms were torticollis, painful spine, and painful and marked limitation of the pelvic movements. Since the intimal and medial thickness of the common carotid artery appears to be a sensitive marker of vascular risk, the proposed standardized method of measuring these parameter may allow early detection and assessment of changes. An independent study of Chinese herb constituents by Takemoto et al. Validation of conversion between mini-mental state examination and montreal cognitive assessment.

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Effect of adrenergic and cholinergic antagonists on post-hemorrhagic erythropoiesis in rats. Dopamine receptor imaging in alcohol dependency: should personality traits be taken into account? Testing for HIV-1 alone would have failed to identify 87 percent of the patients infected with HBV and 80 percent of those infected with HCV. The National Health Insurance Research Database in Taiwan was searched for migraine patients and was also used to select an age- and sex-matched cohort of subjects without migraine. We found a 100-fold reduction in intracellular S1P levels in platelets derived from Sphk2(-/-) mutants compared with Sphk1(-/-) or wild-type mice, as analyzed by mass spectrometry.

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mutans ATCC 25175 adheres to this restorative material, and the topical fluorides did not affect this event. The consequences of aging on the hydrolysis and absorption of hexoses was assessed in vitro using everted intestinal segments. The cellular oxidative stress (balance between pro-oxidant and antioxidant) may be a major risk factor for chronic diseases.

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Halophilic Bacteria of Lunsu Produce an Array of Industrially Important Enzymes with Salt Tolerant Activity. The administration of M-CSF to mice has demonstrated antitumor therapeutic effects in vivo.

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Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation. In the SGA infants, the concentration of alpha-lactalbumin was significantly higher than in the AGA infants of similar gestational age.

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The area under the concentration-time curve (AUC) from zero to 1h, 2h, 3h, tracheal extubation and infinity, the absorption and distribution half-lives, maximum plasma and CSF concentrations, time to the peak concentration of sufentanil, and the fraction of sufentanil that reached the central circulation after epidural administration were assessed. Heterogeneous responses of canine basilar and middle cerebral arteries to serotonin at normal and high CO2 tension.

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It further indicates that type II motion cannot be ruled out as a normal variant. In children with congenital heart disease intimal changes follow. The dose at the apex of the tumour ranged from 30 to 120 Gy (median 93). Cellular uptake and degradation of phosphorothioate oligonucleotides by marine and freshwater ciliates. The author of this communication gathered whole range of important information on 2,173 patients permanently resident in Prague 4 district, in whom the gastroduodenal ulcers were diagnosed in the years 1979-1988.

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The species Leptospira interrogans is the primary agent in human infections, but other pathogenic species, such as L. The incidence of such symptoms of patients and healthy subjects was examined by means of questionnaires. The presence of non-tumor cells inside cancer tissue is one of the causes of errors in cell cycle analysis by DNA flow cytometry. Twelve knees (22 per cent) were rated fair or poor, according to the H.S.S.

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The aetiology has not been fully established: a genetic hypothesis seems most likely given the common association with McCune-Albright syndrome. In this study, all students in the first semester of medicine were invited to participate in a study to identify stress factors via questionnaire (MBI-SS, PSQ, PHQ-9, GAD-7) in the WS 2013/2014.

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Serum lipoids and proteins and carbohydrate metabolism in so-called idiopathic lipoidosis The analysis did not reveal a significant candidate gender by SP gender effect. In many instances, as programs move from one stage to another, there may need to be significant changes in administrative functions, delegation, and perhaps even changes in personnel. The present work is devoted to the development and implementation of a computational framework to perform numerical simulations of low Mach number turbulent flows over complex geometries.

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This review summarizes the available evidence and rationale underlying the spectrum of current practices aimed at preventing thrombosis in the transplant recipient, with a particular focus on risk factors, pathophysiology, and described antithrombotic regimens. ALPHA-AMINO HEPTYLIC ACID, A NEW NATURAL AMINO ACID FROM CLAVICEPS PURPUREA Companion Versus Comparison: Examining Seeking Social Companionship or Social Comparison as Characteristics That Differentiate Happy and Unhappy People. Comparison of frequency of asymptomatic microhematuria in patients with stage 2-4 versus stage 0-1 pelvic organ prolapse. The neighbor-joining tree and estimated divergence time based on these D-loop-like NUMT sequences of M.

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Pathologico-anatomical peculiarities of ischemic heart disease in females The purpose of our present study was to determine the brain cellular localization of Glut 1 during the late newborn stage of development, when brain cellular proliferation and differentiation is highly active. Complications of biomox antibiotic resistance enucleation and evisceration: prevention and treatment.

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Aortogram showed localized dissection of the ascending aorta and moderate degree of aortic regurgitation. Sacral Nerve Stimulation for Pediatric Lower Urinary Tract Dysfunction: Development of a Standardized Pathway with tinzaparin vs warfarin diet Objective Urodynamic Outcomes. The aim of this study was to investigate and compare the activity of masticatory muscle of TMJs in healthy individuals and patients with mild, moderate and severe TMJH. Plasma miR-21 may be a novel biomarker for the diagnosis of AMI.

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In addition, laboratory and clinical data were evaluated and additional immunohistochemical staining with E-Cad was performed in suspicious APA patients with available tissue. Effects of estrogen and vanadate on the proliferation of newly established transformed mouse Leydig cell viratop 800 mg line in vitro.

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Furthermore, DNA synthesis and cellular histone mRNA levels decline in a coordinate manner after inhibition of DNA replication by hydroxyurea treatment. A 16-channel radiofrequency (RF) coil array consisting of eight loop-dipole blocks (16LD) was designed and constructed. The predictive accuracy of the model was assessed using a concordance index (c-index) and calibration curves. As regards LV function puricos 300 mg we found a progressive slowing of relaxation in females and of both contraction and relaxation in males, not related to changes in LV mass.

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To investigate and compare the progression cost of venlafaxine without insurance of medically treated primary open angle glaucoma according to the baseline intraocular pressure (IOP). Folic acid (FA) conjugated PTX-PAnP (PTX-PAnP-FA) could be selectively taken into folate receptor-overexpressed tumor cells. The anatomical description was performed using conventional microtechnique and a light microscope. Therefore, a precise histopathological diagnosis is of utmost importance.

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Within the yolk of both fertile and infertile eggs, the latebra, the neck of the pantoprazole tad 40 mg beipackzettel yaz latebra, and four to six pairs of concentric yolk rings were visible, although the rings were less clearly defined in eggs from hens fed the flax-based diet. Fetal cerebral and renal circulation--a longitudinal study in the 2d half of pregnancy

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Methicillin-resistant Staphylococcus aureus: a 6-month survey in a Lisbon paediatric hospital. Using a nucleocapsid transfection assay developed previously, we showed that the transiently expressed L protein had RNA synthesis activity. COUNTERPOINT: Does Low-Dose Oxygen Expose Patients With COPD to More Radiation-Like Risks Than Patients Without COPD? In groups of rats, the fimbria-fornix was lesioned alone, or combined with a lesion of the dorsal perforant path or the ventral perforant path. The lansoprazole 30 mg vs omeprazole medication staphylococci of a weakly coagulase-positive strain multiplied somewhat more extensively in the kidneys than did the coagulase-negative, but never sufficiently to cause the death of any animal within the period of observation of 1 month.

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Alpha-helix formation of isolated fragments of pancreatic polypeptide After administration of lidocaine and ephedrine, VPC and ST elevation were noted, followed by VT and Vf. The nature of the APC that trigger suppressor circuits and the potential chemical mediators involved are discussed. Presence of CAC and MAC may be useful in identifying HIV-infected individuals at higher risk for death. The effects of pH, micelle concentration, applied voltage medicamento rosuvas 10 mg hydrocodone and temperature on the separation and preliminary quantitative analysis were studied for the determination of theophylline in human plasma.